0
Phase I
Safety & dosing trials
0
Phase II
Efficacy testing
0
Phase III
Pivotal trials
0
Preclinical
In development

Clinical Pipeline

Leading drug candidates across multiple therapeutic areas

Phase III KRAS G12C

ONC-201: KRAS Inhibitor

First-in-class KRAS G12C inhibitor for NSCLC

Enrollment 30%
Phase I CDK2

ONC-305: CDK2 Inhibitor

Selective CDK2 inhibitor overcoming CDK4/6 resistance in HR+ breast cancer.

Enrollment 60%
Phase I BCL-XL

ONC-412: PROTAC Degrader

Targeted protein degradation approach for hematological malignancies with novel mechanism.

Enrollment 30%

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